Literature summary for 4.6.1.18 extracted from

Pouckova, P.; Skvor, J.; Gotte, G.; Vottariello, F.; Slavik, J.T.; Matousek, J.; Laurents, D.V.; Libonati, M.; Soucek, J.
Some biological actions of PEG-conjugated RNase A oligomers (2006), Neoplasma, 53, 79-85.

Search for more literature for 4.6.1.18

Application

Application	Comment	Organism
medicine	the chemical conjugation of polyethylene glycol to the RNase A C-dimer, and to two trimers, decreases the aspermatogenic activity of the oligomers while increasing their inhibitory activity on the growth of human UB900518 amelanotic melanoma transplanted in athymic nude mice. The conjugated RNase A oligomers are devoid of any embryotoxic activity	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	commercial preparation	-

Subunits

Subunits	Comment	Organism
More	the chemical conjugation of polyethylene glycol to the RNase A C-dimer, and to two trimers, decreases the aspermatogenic activity of the oligomers while increasing their inhibitory activity on the growth of human UB900518 amelanotic melanoma transplanted in athymic nude mice. The conjugated RNase A oligomers are devoid of any embryotoxic activity	Bos taurus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)