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Literature summary for 4.6.1.18 extracted from
- Transfer RNA cleavages by onconase reveal unusual cleavage sites (2006), J. Biol. Chem., 281, 12201-12209.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lithobates pipiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 18S rRNA + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? |  |
| 28S rRNA + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
| additional information | predominant cleavage sites for onconase are at UG and GG residues. With the tRNA substrates studied, the predominant cleavages mapin the triplet UGG located in the context of the variable loop or the D-arm of the tRNA | Lithobates pipiens | ? | - |
? | |
| tRNAlys + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
| tRNAMet + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
| tRNAPhe + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
| tRNAVal + H2O | - |
Lithobates pipiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? | |
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