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Literature summary for 4.6.1.18 extracted from

  • Merkley, E.D.; Bernard, B.; Daggett, V.
    Conformational changes below the Tm: molecular dynamics studies of the thermal pretransition of ribonuclease A (2008), Biochemistry, 47, 880-892.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.18

Crystallization (Commentary)

Crystallization (Comment) Organism
explicit-solvent molecular dynamics simulations up to the melting temperature of 64°C. Between 37°C and 47°C, there is a small but significant decrease in the number of native contacts, beta-sheet hydrogen bonding, and deviation of backbone conformation, and an increase in the number of non-native contacts. At 57°C°C and 67°C, a non-native helical segment of residues 15-20 forms Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus P61823
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Source Tissue

Source Tissue Comment Organism Textmining
pancreas
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 Bos taurus
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Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 explicit-solvent molecular dynamics simulations up to the melting temperature of 64°C. Between 37°C and 47°C, there is a small but significant decrease in the number of native contacts, beta-sheet hydrogen bonding, and deviation of backbone conformation, and an increase in the number of non-native contacts. At 57°C and 67°C, a non-native helical segment of residues 15-20 forms Bos taurus