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Literature summary for 4.6.1.18 extracted from
- Stabilization of pancreatic ribonuclease A by immobilization on Sepharose-linked antibodies that recognize the labile region of the enzyme (2001), Biochim. Biophys. Acta, 1548, 114-120.
General Stability
| General Stability | Organism |
|---|---|
| immobilized enzyme retains 40-80% activity when incubated 30 min at 55°C with trypsin | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.017 | - |
pH 5.0, 37°C | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA + H2O | yeast RNA | Homo sapiens | 3'-phosphomononucleotides + 3'-phosphooligonucleotides | - |
? |  |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
soluble and immobilized enzyme | Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 70 | 80 | immobilized enzyme retains a far greater fraction of activity at higher temperature with respect to the soluble enzyme | Homo sapiens |
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