Literature summary for 4.6.1.18 extracted from

Landre, J.B.P.; Hewett, P.W.; Olivot, J.M.; Friedl, P.; Ko, Y.; Sachinidis, A.; Moenner, M.
Human endothelial cells selectively express large amounts of pancreatic-type ribonuclease (RNase 1) (2002), J. Cell. Biochem., 86, 540-552.

Search for more literature for 4.6.1.18

Inhibitors

Inhibitors	Comment	Organism	Structure
HP-RNase antibodies	affinity purified polyclonal antibodies against human pancreatic RNase. 94% inhibition with 50 ng	Homo sapiens
inhibit-Ace	86% inhibition at 6 U/ml	Homo sapiens
ribonuclease inhibitor	RI, 97% inhibition at 6 U/ml	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
18000	26000	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	different degrees of glycosylation. The N-glycosylation generates the molecular heterogeneity	Homo sapiens

Purification (Commentary)

Purification (Comment)	Organism
gel filtration on SP-Sepharose column	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
umbilical vein endothelium	primary culture, HUVEC	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
poly(C) + H2O	35 times more active than with poly(U)	Homo sapiens	3'-CMP + 3'-phosphooligonucleotides	-	?
poly(U) + H2O	-	Homo sapiens	3'-UMP + 3'-oligonucleotides	-	?
RNA + H2O	wheat germ RNA	Homo sapiens	3'-phosphomononucleotides + 3'-phosphooligonucleotides	-	?

Synonyms

Synonyms	Comment	Organism
EC-RNase	-	Homo sapiens

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Release 2023.1 (January 2023)