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Literature summary for 4.6.1.18 extracted from

  • Palmer, R.A.; Moss, D.S.; Haneef, I.; Borkakoti, N.
    An X-ray refinement study on the binding of ribonuclease-A to cytidine-N(3)-oxide 2'-phosphate (1984), Biochim. Biophys. Acta, 785, 81-88.
No PubMed abstract available

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with inhibitor cytidine-N(3)-oxide 2'-phosphate Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
cytidine-N3-oxide 2'-phosphate
-
Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Bos taurus endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic 2',3'-nucleoside monophosphate + H2O second step of hydrolysis is irreversible Bos taurus 3'-phosphomononucleotides
-
ir
RNA + H2O endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA Bos taurus 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?
RNA + H2O first step of hydrolysis is reversible Bos taurus cyclic 2',3'-nucleoside monophosphate
-
r