Literature summary for 4.6.1.15 extracted from

Fraiz, F.J.; Pinto, R.M.; Costas, M.J.; Avalos, M.; Canales, J.; Cabezas, A.; Cameselle, J.C.
Enzymic formation of riboflavin 4',5'-cyclic phosphate from FAD: evidence for a specific low-Km FMN cyclase in rat liver (1998), Biochem. J., 330, 881-888.

No PubMed abstract available

Search for more literature for 4.6.1.15

Inhibitors

Inhibitors	Comment	Organism	Structure
FAD	concentration higher than 0.1 mM	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.006	0.008	FAD	-	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Rattus norvegicus	5737	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mn2+	enzyme-activating cation	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
140000	-	gel filtration	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
FAD	Rattus norvegicus	-	AMP + riboflavin cyclic-4',5'-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	female Wistar rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
13	-	p-nitrophenyl-d-TMP as substrate	Rattus norvegicus

Storage Stability

Storage Stability	Organism
-20°C, 1 mg/ml bovine serum albumin	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
FAD	-	Rattus norvegicus	AMP + riboflavin cyclic-4',5'-phosphate	-	?

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	-	Rattus norvegicus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
9	-	-	Rattus norvegicus

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Release 2023.1 (January 2023)