Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Bordetella pertussis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2',3'-O-bis(5-acetamidoanthraniloyl)-ATP | - |
Bordetella pertussis | |
2',3'-O-bis(5-bromoanthraniloyl)-ADP | - |
Bordetella pertussis | |
2',3'-O-bis(5-bromoanthraniloyl)-ATP | - |
Bordetella pertussis | |
2',3'-O-bis(5-bromoanthraniloyl)-ITP | - |
Bordetella pertussis | |
2',3'-O-bis(5-chloroanthraniloyl)-ATP | - |
Bordetella pertussis | |
2',3'-O-bis(5-chloroanthraniloyl)-ITP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-ADP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-ATP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-CTP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-IDP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-IMP | - |
Bordetella pertussis | |
2',3'-O-bis(5-methylanthraniloyl)-ITP | - |
Bordetella pertussis | |
2',3'-O-bis(5-propylanthraniloyl)-ATP | - |
Bordetella pertussis | |
2',3'-O-bis(5-propylanthraniloyl)-ITP | - |
Bordetella pertussis | |
2',3'-O-bis-anthraniloyl-IMP | - |
Bordetella pertussis | |
3'-O-(5-acetamidoanthraniloyl)-ATP | - |
Bordetella pertussis | |
3'-O-(5-acetamidoanthraniloyl)-ITP | - |
Bordetella pertussis | |
3'-O-(5-bromoanthraniloyl)-ADP | - |
Bordetella pertussis | |
3'-O-(5-bromoanthraniloyl)-ATP | - |
Bordetella pertussis | |
3'-O-(5-bromoanthraniloyl)-ITP | - |
Bordetella pertussis | |
3'-O-(5-chloroanthraniloyl)-ATP | - |
Bordetella pertussis | |
3'-O-(5-chloroanthraniloyl)-ITP | - |
Bordetella pertussis | |
3'-O-(5-propylanthraniloyl)-ATP | - |
Bordetella pertussis | |
3'-O-(5-propylanthraniloyl)-ITP | - |
Bordetella pertussis | |
anthraniloyl-IMP | - |
Bordetella pertussis | |
bis-acetamido-anthraniloyl-ITP | - |
Bordetella pertussis | |
methylanthraniloyl-ADP | - |
Bordetella pertussis | |
methylanthraniloyl-ATP | - |
Bordetella pertussis | |
methylanthraniloyl-CTP | - |
Bordetella pertussis | |
methylanthraniloyl-IDP | - |
Bordetella pertussis | |
methylanthraniloyl-IMP | - |
Bordetella pertussis | |
methylanthraniloyl-ITP | - |
Bordetella pertussis | |
additional information | not inhibited by methylanthraniloyl-IMP and anthraniloyl-IMP | Bordetella pertussis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bordetella pertussis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Bordetella pertussis | 3',5'-cyclic-AMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AC toxin | - |
Bordetella pertussis |
adenylyl cyclase | - |
Bordetella pertussis |
CyaA | - |
Bordetella pertussis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Bordetella pertussis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000126 | - |
2',3'-O-bis(5-bromoanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.000015 | - |
2',3'-O-bis(5-chloroanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.000016 | - |
2',3'-O-bis(5-chloroanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00002 | - |
2',3'-O-bis(5-bromoanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.000091 | - |
2',3'-O-bis(5-bromoanthraniloyl)-ADP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00028 | - |
2',3'-O-bis(5-acetamidoanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00033 | - |
3'-O-(5-bromoanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00035 | - |
3'-O-(5-chloroanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00036 | - |
2',3'-O-bis(5-methylanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0006 | - |
methylanthraniloyl-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0007 | - |
3'-O-(5-chloroanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0007 | - |
2',3'-O-bis(5-propylanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00071 | - |
3'-O-(5-acetamidoanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00082 | - |
3'-O-(5-propylanthraniloyl)-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.00092 | - |
3'-O-(5-bromoanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0011 | - |
methylanthraniloyl-CTP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0021 | - |
2',3'-O-bis(5-propylanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0025 | - |
2',3'-O-bis(5-methylanthraniloyl)-CTP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.003 | - |
2',3'-O-bis(5-methylanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0038 | - |
3'-O-(5-propylanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0043 | - |
methylanthraniloyl-ATP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0048 | - |
3'-O-(5-acetamidoanthraniloyl)-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0065 | - |
2',3'-O-bis(5-methylanthraniloyl)-ADP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0066 | - |
2',3'-O-bis(5-methylanthraniloyl)-IDP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0075 | - |
bis-acetamido-anthraniloyl-ITP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.0087 | - |
3'-O-(5-bromoanthraniloyl)-ADP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.011 | - |
methylanthraniloyl-IDP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.012 | - |
methylanthraniloyl-ADP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.012 | - |
2',3'-O-bis-anthraniloyl-IMP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis | |
0.02 | - |
2',3'-O-bis(5-methylanthraniloyl)-IMP | in 75 mM HEPES/NaOH, pH 7.4, at 25°C | Bordetella pertussis |