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Literature summary for 4.6.1.1 extracted from

  • Werthmann, R.C.; von Hayn, K.; Nikolaev, V.O.; Lohse, M.J.; Buenemann, M.
    Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6 (2009), J. Physiol., 587, 4091-4104.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
forskolin
-
Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ isoforms AC5 and AC6 are inhibited by Ca2+ Homo sapiens
thrombin thrombin transiently inhibits adenylyl cyclase 6 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Homo sapiens
-
3',5'-cyclic-AMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
umbilical vein endothelial cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
Homo sapiens 3',5'-cyclic-AMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
AC5 isoform Homo sapiens
AC6 isoform Homo sapiens
adenylyl cyclase
-
Homo sapiens