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Literature summary for 4.6.1.1 extracted from

  • Ichikawa, S.; Koller, D.L.; Curry, L.R.; Lai, D.; Xuei, X.; Edenberg, H.J.; Hui, S.L.; Peacock, M.; Foroud, T.; Econs, M.J.
    Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults (2009), Calcif. Tissue Int., 84, 97-102.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.1

Cloned(Commentary)

Cloned (Comment) Organism
the ADCY10 gene is located in the region linked to spinal bone mineral density Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information sixteen single-nucleotide polymorphisms distributed throughout the ADCY10 gene are genotyped in two healthy groups of American whites: 1692 premenopausal women and 715 men, genotype association with bone mineral density phenotypes, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble soluble adenylate cyclase isozyme AC10 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP Homo sapiens the enzyme is associated to the bone mineral density and ADCY10 polymorphisms are involved in low spinal bone mineral density in hypercalciuric patients, overview 3',5'-cyclic-AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 isozyme AC10, gene ADCY10
-

Source Tissue

Source Tissue Comment Organism Textmining
bone
-
 Homo sapiens
-
lumbar spine
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Homo sapiens 3',5'-cyclic-AMP + diphosphate
-
 ?
ATP the enzyme is associated to the bone mineral density and ADCY10 polymorphisms are involved in low spinal bone mineral density in hypercalciuric patients, overview Homo sapiens 3',5'-cyclic-AMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
ADCY10
-
 Homo sapiens
adenylate cyclase 10
-
 Homo sapiens
soluble adenylate cyclase
-
 Homo sapiens