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Literature summary for 4.6.1.1 extracted from

  • Yahr, T.L.; Vallis, A.J.; Hancock, M.K.; Barbieri, J.T.; Frank, D.W.
    ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system (1998), Proc. Natl. Acad. Sci. USA, 95, 13899-13904.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.1

Activating Compound

Activating Compound Comment Organism Structure
Calmodulin no detectable stimulation of enzyme activity Pseudomonas aeruginosa
crude extract of cytosolic proteins from CHO cells at least 500fold increased adenylate cyclase activity Pseudomonas aeruginosa

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Pseudomonas aeruginosa

Protein Variants

Protein Variants Comment Organism
D212N mutant with no detectable enzyme activity Pseudomonas aeruginosa
D214N mutant with no detectable enzyme activity Pseudomonas aeruginosa
K81M mutant with no detectable enzyme activity Pseudomonas aeruginosa
K88I mutant with no detectable enzyme activity Pseudomonas aeruginosa
r23ExoY mutant with histidine tag at carboxyl-terminal position, detectable enzyme activity Pseudomonas aeruginosa
rExoY mutant with histidine tag at amino-terminal position, detectable enzyme activity Pseudomonas aeruginosa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41670
-
 predicted after nucleotide sequence analysis Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Pseudomonas aeruginosa 3',5'-cAMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
ExoY
-
 Pseudomonas aeruginosa