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Literature summary for 4.6.1.1 extracted from

  • Drummond, G.I.; Severson, D.L.
    Preparation and characterization of adenylate cyclase from heart and skeletal muscle (1974), Methods Enzymol., 38C, 143-149.
    View publication on PubMed
Search for more literature for 4.6.1.1

Inhibitors

Inhibitors Comment Organism Structure
diphosphate
-
 Cavia porcellus
diphosphate
-
 Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.08
-
 ATP
-
 Cavia porcellus

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+
-
 Cavia porcellus
F-
-
 Cavia porcellus
F-
-
 Oryctolagus cuniculus
Mn2+
-
 Cavia porcellus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
MgATP2- Cavia porcellus at pH 7.5 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Cavia porcellus
-
heart
-
 Oryctolagus cuniculus
-
lung
-
 Cavia porcellus
-
skeletal muscle
-
 Cavia porcellus
-
skeletal muscle
-
 Oryctolagus cuniculus
-

Storage Stability

Storage Stability Organism
-18°C, membrane preparation, lyophilized, 1 week, 50% activity Cavia porcellus
-18°C, membrane preparation, lyophilized, 1 week, 50% activity Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP
-
 Cavia porcellus 3',5'-cAMP + diphosphate
-
 ?
MgATP2- at pH 7.5 Cavia porcellus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8
-
 Cavia porcellus
7 8
-
 Oryctolagus cuniculus
8.5
-
-
 Cavia porcellus
8.5
-
-
 Oryctolagus cuniculus