Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial matrix | - |
Arabidopsis thaliana | 5759 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + hydrogen cyanide | Arabidopsis thaliana | - |
hydrogen sulfide + L-3-cyanoalanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + hydrogen cyanide | - |
Arabidopsis thaliana | hydrogen sulfide + L-3-cyanoalanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CAS | - |
Arabidopsis thaliana |
CYS-C1 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme knockout leads to an increased level of cyanide in the roots and leaves and a severe defect in root hair morphogenesis, suggesting that cyanide acts as a signaling factor in root developmen. The CYS-C1 loss-of-function mutation is not toxic for the plant | Arabidopsis thaliana |
physiological function | cyanide must be rapidly detoxified and metabolized by the plant to maintain the concentration below toxic levels in Arabidopsis plants through the mitochondrial beta-cyanoalanine synthase. During compatible and incompatible plant-bacteria interactions, cyanide accumulation and CYS-C1 gene expression are negatively correlated. Enzyme mutation increases both plant tolerance to biotrophic pathogens and their susceptibility to necrotrophic fungi. The enzyme is essential for maintaining non-toxic concentrations of cyanide in the mitochondria to facilitate cyanide's role in signaling | Arabidopsis thaliana |