Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(3Z)-3-(1,3-benzothiazol-2-yl)-4-(4-methoxyphenyl)but-3-enoic acid | inhibitor based on binding mode of myricetin, contributuion of the Zn2+-chelating group to inhibitory activity | Homo sapiens | |
2-([(4-methoxyphenyl)carbonyl]amino)-1-benzothiophene-3-carboxylic acid | inhibitor based on binding mode of myricetin | Homo sapiens | |
2-([(4-methoxyphenyl)carbonyl]amino)benzoic acid | inhibitor based on binding mode of myricetin | Homo sapiens | |
myricetin | substrate transition-state (Zn2+-bound methylglyoxal-glutathione hemithioacetal) mimetic inhibitor | Homo sapiens | |
S-4-bromobenzylglutathione | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform glyoxalase I | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00056 | - |
pH 7.0, 25°C | Homo sapiens | myricetin | |
0.002 | - |
pH 7.0, 25°C | Homo sapiens | (3Z)-3-(1,3-benzothiazol-2-yl)-4-(4-methoxyphenyl)but-3-enoic acid | |
0.0332 | - |
pH 7.0, 25°C | Homo sapiens | S-4-bromobenzylglutathione | |
0.0546 | - |
pH 7.0, 25°C | Homo sapiens | 2-([(4-methoxyphenyl)carbonyl]amino)-1-benzothiophene-3-carboxylic acid | |
0.0932 | - |
pH 7.0, 25°C | Homo sapiens | 2-([(4-methoxyphenyl)carbonyl]amino)benzoic acid |