Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
crystal sructure of glyoxalase I in complex with S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione and S-p-nitrobenzyloxycarbonylglutathione at 2.0 and 1.72 A, respectively | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-(N-hydroxy-N-methylcarbamoyl)glutathione | - |
Homo sapiens | |
S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione | - |
Homo sapiens | |
S-(N-hydroxy-N-p-iodophenylcarbamoyl)glutathione | - |
Homo sapiens | |
S-p-bromobenzylglutathione | - |
Homo sapiens | |
S-p-nitrobenzyloxycarbonylglutathione | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione-methylglyoxal hemithioacetal | Homo sapiens | glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione | (R)-S-lactoylglutathione | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q04760 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione-methylglyoxal hemithioacetal | glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione | Homo sapiens | (R)-S-lactoylglutathione | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glyoxalase I | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000014 | - |
S-(N-hydroxy-N-p-bromophenylcarbamoyl)glutathione | - |
Homo sapiens | |
0.00008 | - |
S-p-bromobenzylglutathione | - |
Homo sapiens |