Literature summary for 4.4.1.5 extracted from

Ito, M.; Sadakane, K.; Shiotsuki, T.; Eto, M.
Effects of substrate- (glutathione-) and inhibitor- (flavonoid-) analogues on glyoxalase I activity (1992), Biosci. Biotechnol. Biochem., 56, 1461-1462.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
baicalein	-	Saccharomyces cerevisiae
cromoglycate	0.1 mM, 50% inhibition	Saccharomyces cerevisiae
quercetin	-	Saccharomyces cerevisiae
S-(1-naphthylmethyl)-glutathione	-	Saccharomyces cerevisiae
S-(2-chlorobenzyl)-glutathione	-	Saccharomyces cerevisiae
S-(2-hydroxybenzyl)-glutathione	-	Saccharomyces cerevisiae
S-benzyl-glutathione	-	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glutathione + methylglyoxal	-	Saccharomyces cerevisiae	S-lactoylglutathione	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.1	-	chromoglycate	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)