Application | Comment | Organism |
---|---|---|
degradation | enzyme is involved in degradation of primary oxidation products of isoprene, cis-1,2-dichloroethanol, and trans-1,2-dichloroethanol | Rhodococcus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,2-Epoxybutane | addition of low concentrations of 1,2-epoxybutane and 1,2-epoxyhexane strongly inhibits growth on isoprene but not growth on ethanol and irreversibly inhibits the epoxide-degrading activity | Rhodococcus sp. | |
1,2-epoxyhexane | addition of low concentrations of 1,2-epoxybutane and 1,2-epoxyhexane strongly inhibits growth on isoprene but not growth on ethanol and irreversibly inhibits the epoxide-degrading activity | Rhodococcus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(3R)-3,4-epoxy-3-methylbut-1-ene + glutathione | Rhodococcus sp. | - |
2-(glutathion-S-yl)-2-methylbut-3-en-1-ol | - |
? | |
cis-1,2-dichloroepoxyethane + glutathione | Rhodococcus sp. | - |
1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol | - |
? | |
epoxypropane + glutathione | Rhodococcus sp. | - |
2-(glutathion-S-yl)-propan-1-ol | - |
? | |
trans-1,2-dichloroepoxyethane + glutathione | Rhodococcus sp. | - |
1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhodococcus sp. | Q9RBP4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(3R)-3,4-epoxy-3-methylbut-1-ene + glutathione | - |
Rhodococcus sp. | 2-(glutathion-S-yl)-2-methylbut-3-en-1-ol | - |
? | |
cis-1,2-dichloroepoxyethane + glutathione | - |
Rhodococcus sp. | 1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol | - |
? | |
epoxypropane + glutathione | - |
Rhodococcus sp. | 2-(glutathion-S-yl)-propan-1-ol | - |
? | |
trans-1,2-dichloroepoxyethane + glutathione | - |
Rhodococcus sp. | 1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IsoI | - |
Rhodococcus sp. |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is a glutathione S-transferase involved in the metabolism of isoprene and able to detoxify reactive epoxides produced by monooxygenation of chlorinated ethenes | Rhodococcus sp. |