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Literature summary for 4.4.1.26 extracted from

  • Tan, Z.; Clomburg, J.M.; Gonzalez, R.
    Synthetic pathway for the production of olivetolic acid in Escherichia coli (2018), ACS Synth. Biol., 7, 1886-1896 .
    View publication on PubMed

Application

Application Comment Organism
synthesis synthesis of olivetolic acid from a single carbon source through combining OLA synthase and OLA cyclase expression with the required modules of a beta-oxidation reversal for hexanoyl-CoA generation. The use of additional auxiliary enzymes to increase hexanoyl-CoA and malonyl-CoA, along with evaluation of varying fermentation conditions, enables the synthesis of 80 mg/L olivetolic acid Cannabis sativa

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Cannabis sativa

Organism

Organism UniProt Comment Textmining
Cannabis sativa I6WU39
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Synonyms

Synonyms Comment Organism
OAC
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Cannabis sativa