Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | cell treatment with ERK 1/2 specific inhibitor 1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene (U0126) blocks LTC4S expression, pyrrolidine dithiocarbamate inhibits reactive oxygen species generation and NF-?B activation, which in turn blocks LTC4S expression | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Rattus norvegicus | - |
Kupffer cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + glutathione | - |
Rattus norvegicus | leukotriene C4 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
leukotriene C4 synthase | - |
Rattus norvegicus |
LTC4 synthase | - |
Rattus norvegicus |
LTC4S | - |
Rattus norvegicus |