Application | Comment | Organism |
---|---|---|
molecular biology | TNF-alpha exposure downregulates the LTC4 synthase gene expression in monocytes/macrophages via a transcriptional mechanism | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Tumor necrosis factor alpha | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16873 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
leukotriene C4 synthetase | - |
Homo sapiens |
LTC4 synthase | - |
Homo sapiens |
LTC4S | - |
Homo sapiens |