Literature summary for 4.4.1.20 extracted from

Schmidt-Krey, I.; Kanaoka, Y.; Mills, D.J.; Irikura, D.; Haase, W.; Lam, B.K.; Austen, K.F.; Kuehlbrandt, W.
Human leukotriene C4 synthase at 4.5.ANG. resolution in projection (2004), Structure, 12, 2009-2014.

Search for more literature for 4.4.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Schizosaccharomyces pombe	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
resolution of 4.5 A	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
18000	-	3 * 18000, SDS-PAGE, electron crystallography	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
leukotriene C4	Homo sapiens	-	leukotriene A4 + glutathione	-	r

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q16873	-	-

Purification (Commentary)

Purification (Comment)	Organism
the recombinant enzyme from Schizosaccharomyces pombe, to apparent homogeneity	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
leukotriene A4 + glutathione	-	Homo sapiens	leukotriene C4	-	r
leukotriene C4	-	Homo sapiens	leukotriene A4 + glutathione	-	r

Subunits

Subunits	Comment	Organism
trimer	3 * 18000, SDS-PAGE, electron crystallography	Homo sapiens

Synonyms

Synonyms	Comment	Organism
leukotriene C4 synthase	-	Homo sapiens
LTC4 synthase	-	Homo sapiens
LTC4S	-	Homo sapiens

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Release 2023.1 (January 2023)