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Literature summary for 4.4.1.20 extracted from

  • Soederstroem, M.; Morgenstern, R.; Hammarstroem, S.
    Protein-protein interaction affinity chromatography of leukotriene C4 synthase (1995), Protein Expr. Purif., 6, 352-356.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
affinity chromatography purification based on specific interaction between leukotriene C4 synthase and microsomal glutathione S-transferase which ocurs in the presence of magnesium ion Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.729
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 + glutathione
-
Mus musculus leukotriene C4 + H2O
-
?
leukotriene A4 + glutathione
-
Homo sapiens leukotriene C4 + H2O
-
?

Subunits

Subunits Comment Organism
More the major components migrate as 18000 Da, 37000 Da, 48000 Da and 60000 Da proteins in SDS-PAGE Homo sapiens