BRENDA - Enzyme Database
show all sequences of 4.4.1.2

Trichomonas species: homocysteine desulphurase and serine sulphydrase activities

Thong, K.W.; Coombs, G.H.; Exp. Parasitol. 63, 143-151 (1987)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
2,2'-dithiodiethylanol
-
Trichomonas vaginalis
2,4-Dichlorophenol
-
Trichomonas vaginalis
bithionol
-
Trichomonas vaginalis
Dichlorophene
-
Trichomonas vaginalis
DL-propargylglycine
-
Trichomonas vaginalis
Hexachlorophene
-
Trichomonas vaginalis
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.549
-
homocysteine
-
Trichomonas vaginalis
Organism
Organism
UniProt
Commentary
Textmining
no activity in Trichomitus batrachorum
-
-
-
no activity in Trichomonas foetus
-
-
-
Pentatrichomonas hominis
-
-
-
Trichomonas vaginalis
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
L-homocysteine + H2O
-
34598
Trichomonas vaginalis
H2S + NH3 + 2-oxobutanoate
-
34598
Trichomonas vaginalis
?
L-homocysteine + H2O
-
34598
Pentatrichomonas hominis
H2S + NH3 + 2-oxobutanoate
-
34598
Pentatrichomonas hominis
?
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2,2'-dithiodiethylanol
-
Trichomonas vaginalis
2,4-Dichlorophenol
-
Trichomonas vaginalis
bithionol
-
Trichomonas vaginalis
Dichlorophene
-
Trichomonas vaginalis
DL-propargylglycine
-
Trichomonas vaginalis
Hexachlorophene
-
Trichomonas vaginalis
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.549
-
homocysteine
-
Trichomonas vaginalis
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
L-homocysteine + H2O
-
34598
Trichomonas vaginalis
H2S + NH3 + 2-oxobutanoate
-
34598
Trichomonas vaginalis
?
L-homocysteine + H2O
-
34598
Pentatrichomonas hominis
H2S + NH3 + 2-oxobutanoate
-
34598
Pentatrichomonas hominis
?
Other publictions for EC 4.4.1.2
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
722937
El-Sayed
Characterization of homocystei ...
Aspergillus fumigatus, Aspergillus fumigatus ASH JX006238
J. Microbiol. Biotechnol.
23
499-510
2013
1
1
-
-
1
-
7
3
1
-
1
2
-
2
-
-
1
-
-
-
2
-
13
1
1
1
-
6
3
1
-
3
-
-
1
-
1
1
-
-
-
1
-
-
7
-
3
1
-
1
2
-
-
-
1
-
-
2
-
13
1
1
-
6
3
1
-
3
1
-
-
-
-
-
-
34598
Thong
Trichomonas species: homocyste ...
no activity in Trichomitus batrachorum, no activity in Trichomonas foetus, Pentatrichomonas hominis, Trichomonas vaginalis
Exp. Parasitol.
63
143-151
1987
-
-
-
-
-
-
6
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
34599
Thong
-
Homocysteine desulphurase acti ...
no activity in Crithidia fasciculata, no activity in Entamoeba histolytica, no activity in Escherichia coli, no activity in Herpetomonas muscarum, no activity in Leishmania mexicana mexicana, no activity in Leishmania tarentolae, no activity in mouse, no activity in Tetrahymena pyriformis, no activity in Trichomonas foetus, Trichomonas batrachorum, Trichomonas vaginalis
IRCS Med. Sci. Libr. Compend.
13
493-494
1985
-
-
-
-
-
-
4
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
34600
Kallio
Function of pyridoxal phosphat ...
Morganella morganii
J. Biol. Chem.
192
371-377
1951
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
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-
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-
-
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-
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-
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-
-
-
-
-
-
-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-