Cloned (Comment) | Organism |
---|---|
expression of ACC synthase in Escherichia coli | Malus domestica |
Protein Variants | Comment | Organism |
---|---|---|
E47D | 3.8% of wild-type ACC synthase activity | Malus domestica |
E47Q | 0.9% of wild-type ACC synthase activity | Malus domestica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-Vinylglycine | mechanism-based inactivation | Malus domestica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.026 | - |
(S,S)-S-adenosylmethionine | alpha,gamma-elimination | Malus domestica | |
0.037 | - |
(R,S)-S-adenosylmethionine | beta,gamma-elimination | Malus domestica | |
0.27 | - |
L-Vinylglycine | deamination | Malus domestica | |
37 | - |
alanine | transamination | Malus domestica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine | Malus domestica | - |
1-aminocyclopropane-1-carboxylate + methylthioadenosine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Malus domestica | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant ACC synthase | Malus domestica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R,S)-S-adenosyl-L-methionine | - |
Malus domestica | vinylglycine + methylthioadenosine | - |
? | |
(S,S)-S-adenosyl-L-methionine | - |
Malus domestica | 1-aminocyclopropane-1-carboxylate + methylthioadenosine | - |
? | |
L-vinylglycine | - |
Malus domestica | alpha-ketobutyrate + ammonia | - |
? | |
pyridoxal 5'-phosphate + alanine | - |
Malus domestica | pyridoxamine 5'-phosphate + pyruvate | - |
? | |
S-adenosyl-L-methionine | - |
Malus domestica | 1-aminocyclopropane-1-carboxylate + methylthioadenosine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACC synthase | - |
Malus domestica |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.019 | - |
alanine | transamination | Malus domestica | |
0.079 | - |
(R,S)-S-adenosylmethionine | beta,gamma-elimination | Malus domestica | |
0.7 | 1 | L-Vinylglycine | deamination | Malus domestica | |
0.71 | - |
L-Vinylglycine | deamination | Malus domestica | |
18 | - |
(S,S)-S-adenosylmethionine | alpha,gamma-elimination | Malus domestica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Malus domestica |