Application | Comment | Organism |
---|---|---|
medicine | the enzyme is important for bacterial virulence and is therefor a potential target for antibacterial drug development | Salmonella enterica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme is not inhibited by pyridamine antimicrobial agents (pyrimethanil, cyprodinil or mepanipyrim) | Salmonella enterica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.38 | - |
cystathionine | - |
Salmonella enterica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Salmonella enterica | the enzyme catalyzes the penultimate step in methionine biosynthesis. The enzyme is important for bacterial virulence | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica | - |
serovar typhimurium | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cystathionine + H2O | - |
Salmonella enterica | L-homocysteine + NH3 + pyruvate | - |
? | |
additional information | the enzyme catalyzes the penultimate step in methionine biosynthesis. The enzyme is important for bacterial virulence | Salmonella enterica | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.5 | - |
cystathionine | - |
Salmonella enterica |