Literature summary for 4.4.1.13 extracted from

Morinaga, Y.; Tani, Y.; Yamada, H.
Biosynthesis of homocysteine in a facultative methylotroph, Pseudomonas FM518 (1983), Agric. Biol. Chem., 47, 2855-2860.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
L-Met	competitive	Pseudomonas sp.
S-adenosylmethionine	weak	Pseudomonas sp.

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas sp.	-	FM518	-
Pseudomonas sp. FM518	-	FM518	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-cystathionine + H2O	-	Pseudomonas sp.	L-homocysteine + NH3 + pyruvate	-	?
L-cystathionine + H2O	-	Pseudomonas sp. FM518	L-homocysteine + NH3 + pyruvate	-	?

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	required as cofactor	Pseudomonas sp.

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Release 2023.1 (January 2023)