Cloned (Comment) | Organism |
---|---|
- |
Pseudomonas putida |
Crystallization (Comment) | Organism |
---|---|
in mutant C116H a loop structure (Ala51-Asn64) in the adjacent subunit of the catalytic dimer cannot approach the cofactor pyridoxal 5'-phosphate because His116 disrupts the interaction of Asp241 with Lys240, and the liberated side chain of Lys240 causes steric hindrance with this loop | Pseudomonas putida |
Protein Variants | Comment | Organism |
---|---|---|
C116H | mutation renders the enzyme inactive towards L-methionine, but activity is restored when the substrate is homocysteine due to substrate-assisted catalysis | Pseudomonas putida |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas putida | P13254 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
MdeA | - |
Pseudomonas putida |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Pseudomonas putida |