Cloned (Comment) | Organism |
---|---|
transfection into HEK-293 cells | Homo sapiens |
transfection into HEK-293 cells | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P32929 | - |
- |
Mus musculus | Q8VCN5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Mus musculus | - |
aortic endothelial cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CSEgamma | - |
Homo sapiens |
CSEgamma | - |
Mus musculus |
CTH | - |
Homo sapiens |
CTH | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | aortas from atherogenic apolipoprotein E knockout mice fed a high-fat diet show reduced CSEgamma mRNA expression and protein abundance | down |
Homo sapiens | human aortic endothelial cells exposed to oxidized LDL show reduced CSEgamma mRNA expression and protein abundance | down |
Homo sapiens | CSEgamma expression is upregulated by pan-histone deacetylase inhibitors and by class II-specific HDAC inhibitors, but not by other class-specific inhibitors. The histone deacetylase 6 selective inhibitor tubacin and histone deacetylase 6-specific siRNA increase CSEgamma expression and block oxidized LDL-mediated reductions in endothelial CSEgamma expression and CSEgamma promoter activity | up |
General Information | Comment | Organism |
---|---|---|
physiological function | aortas from atherogenic apolipoprotein E knockout mice fed a high-fat diet show reduced CSEgamma mRNA expression and protein abundance | Mus musculus |
physiological function | CSEgamma expression is upregulated by pan-histone deacetylase inhibitors and by class II-specific HDAC inhibitors, but not by other class-specific inhibitors. The histone deacetylase 6 selective inhibitor tubacin and histone deacetylase 6-specific siRNA increase CSEgamma expression and block oxidized LDL-mediated reductions in endothelial CSEgamma expression and CSEgamma promoter activity | Homo sapiens |