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Literature summary for 4.4.1.1 extracted from
- Rhodanese, but not cystathionine-gamma-lyase, is associated with dextran sulfate sodium-evoked colitis in mice: a sign of impaired colonic sulfide detoxification? (2009), Toxicology, 264, 96-103.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | CSE is not associated with dextran sulfate sodium-induced colitis in mice | Rattus norvegicus |
| medicine | CSE is not associated with dextran sulfate sodium-induced colitis in mice | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| DL-propargylglycine | - |
Mus musculus |  |
| DL-propargylglycine | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 44000 | - |
SDS-PAGE | Rattus norvegicus |
| 44000 | - |
SDS-PAGE | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| colon | - |
Rattus norvegicus | - |
| colon | - |
Mus musculus | - |
| feces | - |
Rattus norvegicus | - |
| feces | - |
Mus musculus | - |
| kidney | - |
Rattus norvegicus | - |
| kidney | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-cysteine + H2O | - |
Rattus norvegicus | sulfide + NH3 + pyruvate | - |
? | |
| L-cysteine + H2O | - |
Mus musculus | sulfide + NH3 + pyruvate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CSE | - |
Rattus norvegicus |
| CSE | - |
Mus musculus |
| cysteine desulfhydrase | - |
Rattus norvegicus |
| cysteine desulfhydrase | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
| pyridoxal 5'-phosphate | - |
Mus musculus | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | CSE activity and protein levels in the colonic tissue do not notably change in the mice with colitis | additional information |
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