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Literature summary for 4.4.1.1 extracted from

  • Li, X.; Jin, H.; Bin, G.; Wang, L.; Tang, C.; Du, J.
    Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow (2009), Exp. Biol. Med., 234, 504-512.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
DL-propargylglycine irreversible inhibitor of CSE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-cysteine + H2O Rattus norvegicus
-
sulfide + NH3 + pyruvate
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cysteine + H2O
-
Rattus norvegicus sulfide + NH3 + pyruvate
-
?

Synonyms

Synonyms Comment Organism
CSE
-
Rattus norvegicus
cystathionine-gamma-lyase
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Rattus norvegicus

General Information

General Information Comment Organism
metabolism CSE is a key enzyme in the pathway of cystathionine metabolism to produce endogenous H2S Rattus norvegicus