Activating Compound | Comment | Organism | Structure |
---|---|---|---|
calcium-calmodulin | catalytic activity of pure CSE is increased more than 2fold by calcium and calmodulin, but not by either substance alone | Mus musculus |
Application | Comment | Organism |
---|---|---|
additional information | H2S is a physiologic vasodilator and regulator of blood pressure | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | CSE-/- mice and CSE-/+ mice, mice genetically deficient in this enzyme display marked hypertension, comparable to that of eNOS-/- mice | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DL-propargylglycine | elevates blood pressure | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Mus musculus | - |
blood vessel | predominantly localized to the endothelial layer of blood vessels | Mus musculus | - |
endothelial cell | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
serum | - |
Mus musculus | - |
vascular system | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
CSE | - |
Mus musculus |
cystathionine gamma-lyase | - |
Mus musculus |