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Literature summary for 4.4.1.1 extracted from

  • Patel, P.; Vatish, M.; Heptinstall, J.; Wang, R.; Carson, R.J.
    The endogenous production of hydrogen sulphide in intrauterine tissues (2009), Reprod. Biol. Endocrinol., 7, 10.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information NO increases the production of hydrogen sulphide in fetal membranes. Presence of 10 mM L-cysteine increases H2S production rate. Low oxygen levels increases H2S production rates Rattus norvegicus
additional information presence of 10 mM L-cysteine increases H2S production rate. Low oxygen levels increases H2S production rates Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
Western blot Homo sapiens
43000
-
Western blot Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens hydrogen sulfide is a gas signalling molecule which is produced endogenously from L-cysteine ?
-
?
additional information Rattus norvegicus hydrogen sulfide is a gas signalling molecule which is produced endogenously from L-cysteine ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
pregnant and nonpregnant Sprague-Dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
fetal membrane order of hydrogen sulfide production rates for different tissues are: liver (777 nM/min/g), followed by uterus (168 nM/min/g), fetal membranes (22.3 nM/min/g), placenta (11.1 nM/min/g), compared to human placenta (200 nM/min/g) Rattus norvegicus
-
liver order of hydrogen sulfide production rates for different tissues are: liver (777 nM/min/g), followed by uterus (168 nM/min/g), fetal membranes (22.3 nM/min/g), placenta (11.1 nM/min/g), compared to human placenta (200 nM/min/g) Rattus norvegicus
-
placenta
-
Homo sapiens
-
placenta order of hydrogen sulfide production rates for different tissues are: liver (777 nM/min/g), followed by uterus (168 nM/min/g), fetal membranes (22.3 nM/min/g), placenta (11.1 nM/min/g), compared to human placenta (200 nM/min/g) Rattus norvegicus
-
uterine smooth muscle order of hydrogen sulfide production rates for different tissues are: liver (777 nM/min/g), followed by uterus (168 nM/min/g), fetal membranes (22.3 nM/min/g), placenta (11.1 nM/min/g), compared to human placenta (200 nM/min/g) Rattus norvegicus
-
uterus
-
Homo sapiens
-
uterus order of hydrogen sulfide production rates for different tissues are: liver (777 nM/min/g), followed by uterus (168 nM/min/g), fetal membranes (22.3 nM/min/g), placenta (11.1 nM/min/g), compared to human placenta (200 nM/min/g) Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cysteine + H2O
-
Homo sapiens sulfide + NH3 + pyruvate
-
?
L-cysteine + H2O
-
Rattus norvegicus sulfide + NH3 + pyruvate
-
?
additional information hydrogen sulfide is a gas signalling molecule which is produced endogenously from L-cysteine Homo sapiens ?
-
?
additional information hydrogen sulfide is a gas signalling molecule which is produced endogenously from L-cysteine Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
CSE
-
Homo sapiens
CSE
-
Rattus norvegicus
cystathionine gamma-lyase
-
Homo sapiens
cystathionine gamma-lyase
-
Rattus norvegicus