Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | testosterone incubation of rat aorta does not change CSE expression. Testosterone modulates H2S levels by increasing the enzymatic conversion of L-cysteine to H2S | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Beta-cyano-L-alanine | 10 mM inhibits testosterone induced H2S biosynthesis | Rattus norvegicus | |
propargylglycine | 10 mM inhibits testosterone induced H2S biosynthesis | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + H2O | - |
Rattus norvegicus | sulfide + NH3 + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CSE | - |
Rattus norvegicus |
cystathionine gamma lyase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |