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Literature summary for 4.4.1.1 extracted from

  • Liu, G.; Casqueiro, J.; Banuelos, O.; Cardoza, R.E.; Gutierrez, S.; Martin, J.F.
    Targeted inactivation of the mecB gene, encoding cystathionine-gamma-lyase, shows that the reverse transsulfuration pathway is required for high-level cephalosporin biosynthesis in Acremonium chrysogenum C10 but not for methionine induction of the cephalosporin genes (2001), J. Bacteriol., 183, 1765-1772.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information gene disruption mutants, lower cephalosporin production in Shenย’s defined fermentation medium supplemented with methionine, but not in the same medium without methionine Acremonium chrysogenum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Acremonium chrysogenum enzyme activity is required for high-level cephalosporin biosynthesis but not for low-level production of the antibiotic ?
-
?
additional information Acremonium chrysogenum C10 / ATCC 48272 enzyme activity is required for high-level cephalosporin biosynthesis but not for low-level production of the antibiotic ?
-
?

Organism

Organism UniProt Comment Textmining
Acremonium chrysogenum
-
C10
-
Acremonium chrysogenum C10 / ATCC 48272
-
C10
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme activity is required for high-level cephalosporin biosynthesis but not for low-level production of the antibiotic Acremonium chrysogenum ?
-
?
additional information enzyme activity is required for high-level cephalosporin biosynthesis but not for low-level production of the antibiotic Acremonium chrysogenum C10 / ATCC 48272 ?
-
?