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Literature summary for 4.4.1.1 extracted from

  • Steegborn, C.; Clausen, T.; Sondermann, P.; Jacob, U.; Worbs, M.; Marinkovic, S.; Huber, R.; Wahl, M.C.
    Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration (1999), J. Biol. Chem., 274, 12675-12684.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
aminoethoxyvinylglycine
-
Homo sapiens
propargylglycine
-
Homo sapiens
trifluoro-Ala
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.5
-
L-cystathionine
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cystathionine + H2O
-
Homo sapiens ?
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.9
-
cystathionine
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.7
-
-
Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
8 9 pH 8.0: about 85% of maximal activity, pH 9.0: about 50% of maximal activity Homo sapiens