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Literature summary for 4.4.1.1 extracted from

  • Fearon, C.W.; Rodkey, J.A.; Abeles, R.H.
    Identification of the active-site residue of gamma-cystathionase labeled by the suicide inactivator beta, beta, beta-trifluoroalanine (1982), Biochemistry, 21, 3790-3794.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
beta,beta,beta-trifluoroalanine the epsilon-NH2 group of the active-site Lys forms a Schiff base with pyridoxal 5'phosphate is capable of interacting with the beta carbon of the suicide inactivator beta,beta,beta-trifluoroalanine Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate the epsilon-NH2 group of the active-site Lys forms a Schiff base with pyridoxal 5'phosphate. The enzyme contains the sequence -Ser-X-X-Lys(pyridoxal-5'-phosphate) Rattus norvegicus