Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-lysine | no significant conformational change between the pyruvate-bound and (S)-lysine-bound enzyme, presence of substrate has substantial effect on the nature of enzyme-inhibitor association, solvent plays a key role in binding of inhibitor | Sinorhizobium meliloti |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sinorhizobium meliloti | Q07607 | L5-30 | - |
Sinorhizobium meliloti L5-30 | Q07607 | L5-30 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
titration of (S)-lysine into buffered solutions of MosA protein in the presence or absence of saturating amounts of pyruvate, thermodynamic data for (S)-Lysine binding to MosA protein, non-competitive mechanism with substrate-dependent differences in the energetics of inhibitor binding | Sinorhizobium meliloti |
Synonyms | Comment | Organism |
---|---|---|
DHDPS | - |
Sinorhizobium meliloti |
MosA protein | - |
Sinorhizobium meliloti |