Application | Comment | Organism |
---|---|---|
medicine | anti-arrhythmic ajmaline agents | Rauvolfia serpentina |
synthesis | involved in the biosynthesis of almost all plant monoterpenoid indole alkaloids | Rauvolfia serpentina |
Cloned (Comment) | Organism |
---|---|
cloned with His-tag, expression in Escherichia coli strain M15, after expression and Ni-NTA column removed by DAPase | Rauvolfia serpentina |
Crystallization (Comment) | Organism |
---|---|
crystals of free STR1 and co-crystallization of STR1 and tryptamine, 2.95 A and 2.38 A under cryoconditions, crystal growing by hanging drop vapor diffusion, 302-304 K, 0.8 M potassium sodium tartrate tetrahydrate, pH 7.5 - 8.0, multiple wavelength anomalous dispersion method | Rauvolfia serpentina |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rauvolfia serpentina | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column, Mono Q column, concentration to 10 mg/ml in 10 mM Tris-HCl pH 8.0 before crystallization | Rauvolfia serpentina |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tryptamine + secologanin | - |
Rauvolfia serpentina | 3alpha(S)-strictosidine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
STR1 | - |
Rauvolfia serpentina |