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Literature summary for 4.3.2.9 extracted from

  • Gromov, P.; Gromova, I.; Friis, E.; Timmermans-Wielenga, V.; Rank, F.; Simon, R.; Sauter, G.; Moreira, J.M.
    Proteomic profiling of mammary carcinomas identifies C7orf24, a gamma-glutamyl cyclotransferase, as a potential cancer biomarker (2010), J. Proteome Res., 9, 3941-3953.
    View publication on PubMed
Search for more literature for 4.3.2.9

Application

Application Comment Organism
medicine enzyme overexpression defines a subgroup of breast tumors with poor clinical outcome. The enzyme is a cancer biomarker and a serological marker Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal cortex moderate expression Homo sapiens
-
alveolus weak expression Homo sapiens
-
breast adenocarcinoma cell line
-
 Homo sapiens
-
breast cancer cell
-
 Homo sapiens
-
breast luminal epithelial cell weak expression Homo sapiens
-
cerebellum weak expression in granular and molecular layers Homo sapiens
-
cerebral cortex weak expression Homo sapiens
-
cervical cancer cell
-
 Homo sapiens
-
colon epithelium weak expression Homo sapiens
-
colonic adenocarcinoma cell
-
 Homo sapiens
-
colonic cancer cell
-
 Homo sapiens
-
endometrium moderate expression Homo sapiens
-
epithelium mammary gland epithelium Homo sapiens
-
esophageal squamous epithelium weak expression Homo sapiens
-
hepatocyte weak expression Homo sapiens
-
Leydig cell weak expression Homo sapiens
-
lung cancer cell
-
 Homo sapiens
-
mammary gland
-
 Homo sapiens
-
additional information not detected in bone marrow, eye, Fallopian tube, heart, ovary, pancreas, pituitary gland, skin, spinal cord, thymus, placenta, and prostate gland Homo sapiens
-
myocyte striated muscle, weak expression Homo sapiens
-
parathyroid weak/moderate expression Homo sapiens
-
rectal epithelium weak expression Homo sapiens
-
renal tubule moderate expression Homo sapiens
-
serum
-
 Homo sapiens
-
small intestine epithelium weak expression Homo sapiens
-
spleen weak expression Homo sapiens
-
stomach epithelium weak/moderate expression Homo sapiens
-
thyroid gland moderate expression Homo sapiens
-
tonsil weak expression Homo sapiens
-
urethra weak/moderate expression Homo sapiens
-
urinary bladder cancer cell
-
 Homo sapiens
-
uterine cervix weak expression Homo sapiens
-

Synonyms

Synonyms Comment Organism
C7orf24
-
 Homo sapiens
gamma-glutamyl cyclotransferase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is upregulated in cancer cells (58% in cervical, 38% in lung, 72% in colon, and 46% in breast cancer) up