Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0023 | 0.004 | dansyl-Tyr-Val-Gly | 37°C, pH 6 | Rattus norvegicus | |
0.035 | 0.048 | Dansyl-Tyr-Val-alpha-hydroxyglycine | 37°C, pH 7.0 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Rattus norvegicus | - |
- |
soluble | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
75000 | - |
truncated type A enzyme which catalyzes a two-step reaction involving an initial hydroxylation of peptidyl-Gly followed by conversion of the peptidyl-alpha-hydroxyglycine intermediate to the amidated product | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
truncated type A enzyme which catalyzes a two-step reaction involving an initial hydroxylation of peptidyl-Gly followed by conversion of the peptidyl-alpha-hydroxyglycine intermediate to the amidated product, enzyme is secreted into the medium from mouse C127 cells transfected with the rat MTC cDNA encoding the truncated type A enzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
medullary thyroid carcinoma cell | enzyme is secreted into the medium from mouse C127 cells transfected with the rat MTC cDNA encoding the truncated type A enzyme | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.25 | 0.32 | dansyl-Tyr-Val-Gly as substrate | Rattus norvegicus |
4.5 | 8.3 | dansyl-Tyr-Val-alpha-hydroxyglycine as substrate | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dansyl-Tyr-Val-alpha-hydroxyglycine | - |
Rattus norvegicus | dansyl-Tyr-Val-NH2 + glyoxylate | - |
? | |
dansyl-Tyr-Val-Gly | - |
Rattus norvegicus | dansyl-Tyr-Val-NH2 + glyoxylate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |