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Literature summary for 4.3.2.3 extracted from

  • Fujiwara, S.; Noguchi, T.
    Degradation of purines: only ureidoglycollate lyase out of four allantoin-degrading enzymes is present in mammals (1995), Biochem. J., 312, 315-318.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
17
-
ureidoglycolate
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-
mitochondrion
-
Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
2 * 33000, SDS-PAGE Rattus norvegicus
64000
-
sucrose density gradient centrifugation Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ureidoglycolate Rattus norvegicus enzyme is involved in allantoin degradation ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
liver enzyme Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Rattus norvegicus
-
brain
-
Rattus norvegicus
-
cardiac muscle
-
Rattus norvegicus
-
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
lung
-
Rattus norvegicus
-
pancreas
-
Rattus norvegicus
-
submandibular gland
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
191
-
-
Rattus norvegicus

Storage Stability

Storage Stability Organism
-20°C, stable for 3 months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ureidoglycolate
-
Rattus norvegicus glyoxylate + urea
-
?
ureidoglycolate enzyme is involved in allantoin degradation Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 33000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
-
Rattus norvegicus