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Literature summary for 4.3.1.3 extracted from

  • Merkel, D.; Retey, J.
    Further insight into the mechanism of the irreversible inhibition of histidine ammonia-lyase by L-cysteine and dioxygen (2000), Helv. Chim. Acta, 83, 1151-1160.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Pseudomonas putida

Inhibitors

Inhibitors Comment Organism Structure
L-cysteine 10 mM, complete inactivation after 3 h under aerobic conditions Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-histidine Pseudomonas putida
-
urocanate + NH3
-
r

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant histidase Pseudomonas putida

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-histidine
-
Pseudomonas putida urocanate + NH3
-
r

Synonyms

Synonyms Comment Organism
HAL
-
Pseudomonas putida