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Literature summary for 4.3.1.3 extracted from
- Histidine ammonia-lyase from Streptomyces griseus (1992), Gene, 115, 19-25.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CN- | KCN | Streptomyces griseus |  |
| D-histidine | competitive | Streptomyces griseus | |
| histidinol phosphate | competitive | Streptomyces griseus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.6 | - |
L-histidine | - |
Streptomyces griseus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 53000 | - |
4 * 53000, calculation from sequence of amino acid | Streptomyces griseus |
| 55000 | - |
4 * 55000, denaturing PAGE | Streptomyces griseus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces griseus | - |
NRRL B-2682 | - |
| Streptomyces griseus NRRL B-2682 | - |
NRRL B-2682 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidine | natural substrate | Streptomyces griseus | urocanate + NH3 | - |
? | |
| L-histidine | non-oxidative deamination | Streptomyces griseus | urocanate + NH3 | - |
? | |
| L-histidine | natural substrate | Streptomyces griseus NRRL B-2682 | urocanate + NH3 | - |
? | |
| L-histidine | non-oxidative deamination | Streptomyces griseus NRRL B-2682 | urocanate + NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 53000, calculation from sequence of amino acid | Streptomyces griseus |
| tetramer | 4 * 55000, denaturing PAGE | Streptomyces griseus |
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