Activating Compound | Comment | Organism | Structure |
---|---|---|---|
GSH | increases at concentrations below 5 mM, pH 7.4 | Cavia porcellus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) | - |
Cavia porcellus | |
dithiothreitol | 20 mM, liver and epidermal enzyme, restored by addition with Zn2+ | Cavia porcellus | |
EDTA | 0.04 mM, liver and epidermal enzyme, restored by incubation with Zn2+ | Cavia porcellus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.36 | - |
L-histidine | pH 9.2 and pH 7.0, epidermal enzyme | Cavia porcellus | |
0.55 | - |
L-histidine | pH 9.2, liver enzyme | Cavia porcellus | |
1 | - |
L-histidine | pH 7.0, liver enzyme | Cavia porcellus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Cavia porcellus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
220000 | - |
gel-permeation chromatography, liver and epidermis enzyme | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | isoenzyme | Cavia porcellus | - |
epidermis | stratum granulosum | Cavia porcellus | - |
epidermis | stratum corneum | Cavia porcellus | - |
liver | isoenzyme | Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | natural substrate | Cavia porcellus | urocanate + NH3 | - |
? |