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Literature summary for 4.3.1.24 extracted from

  • Miziak, P.; Zon, J.; Amrhein, N.; Gancarz, R.
    Inhibitors of phenylalanine ammonia-lyase: substituted derivatives of 2-aminoindane-2-phosphonic acid and 1-aminobenzylphosphonic acid (2007), Phytochemistry, 68, 407-415.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-amino-4-bromoindane-2-phosphonic acid
-
Fagopyrum esculentum
2-amino-4-hydroxyindane-2-phosphonic acid
-
Fagopyrum esculentum
2-aminoindane-2-phosphonic acid
-
Fagopyrum esculentum

Organism

Organism UniProt Comment Textmining
Fagopyrum esculentum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hypocotyl
-
Fagopyrum esculentum
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00008
-
2-aminoindane-2-phosphonic acid
-
Fagopyrum esculentum
0.00009
-
2-amino-4-bromoindane-2-phosphonic acid
-
Fagopyrum esculentum
0.00195
-
2-amino-4-hydroxyindane-2-phosphonic acid
-
Fagopyrum esculentum

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0015
-
-
Fagopyrum esculentum 2-aminoindane-2-phosphonic acid
0.0339
-
-
Fagopyrum esculentum 2-amino-4-bromoindane-2-phosphonic acid
0.06
-
-
Fagopyrum esculentum 2-amino-4-hydroxyindane-2-phosphonic acid