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Literature summary for 4.3.1.22 extracted from
- Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine (2007), Res. Microbiol., 158, 506-511.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.21 | - |
3,4-dihydroxy-L-phenylalanine | - |
Cereibacter sphaeroides |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 39000 | - |
1 * 110000 + 1 * 82000 + 1 * 43000 + 1 * 39000, SDS-PAGE | Cereibacter sphaeroides |
| 43000 | - |
1 * 110000 + 1 * 82000 + 1 * 43000 + 1 * 39000, SDS-PAGE | Cereibacter sphaeroides |
| 82000 | - |
1 * 110000 + 1 * 82000 + 1 * 43000 + 1 * 39000, SDS-PAGE | Cereibacter sphaeroides |
| 110000 | - |
1 * 110000 + 1 * 82000 + 1 * 43000 + 1 * 39000, SDS-PAGE | Cereibacter sphaeroides |
| 274000 | - |
non-denaturing PAGE | Cereibacter sphaeroides |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cereibacter sphaeroides | - |
- |
- |
| Cereibacter sphaeroides OU5 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Cereibacter sphaeroides |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3,4-dihydroxy-L-phenylalanine + NADH | - |
Cereibacter sphaeroides | 3,4-dihydroxyphenylpropanoate + NAD+ + NH3 | - |
? | |
| 3,4-dihydroxy-L-phenylalanine + NADH | - |
Cereibacter sphaeroides OU5 | 3,4-dihydroxyphenylpropanoate + NAD+ + NH3 | - |
? | |
| 3,4-dihydroxy-L-phenylalanine + NADPH | activity with NADPH is less than 40% of the activity with NADH | Cereibacter sphaeroides | 3,4-dihydroxyphenylpropanoate + NADP+ + NH3 | - |
? | |
| 3,4-dihydroxy-L-phenylalanine + NADPH | activity with NADPH is less than 40% of the activity with NADH | Cereibacter sphaeroides OU5 | 3,4-dihydroxyphenylpropanoate + NADP+ + NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 1 * 110000 + 1 * 82000 + 1 * 43000 + 1 * 39000, SDS-PAGE | Cereibacter sphaeroides |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DOPA-reductive deaminase | - |
Cereibacter sphaeroides |
| DOPARDA | - |
Cereibacter sphaeroides |
| reductive deaminase | - |
Cereibacter sphaeroides |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Cereibacter sphaeroides |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Cereibacter sphaeroides |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | required | Cereibacter sphaeroides | |
| NADPH | less than 40% of the activity with NADH | Cereibacter sphaeroides | |
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Release 2023.1 (January 2023)
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