Cloned (Comment) | Organism |
---|---|
gene tcdB, phylogenetic analysis of threonine ammonia-lyases | Geobacter sulfurreducens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | TcdB is not inhibited by isoleucine | Geobacter sulfurreducens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-threonine | Geobacter sulfurreducens | a step in the pathway for the biosynthesis of isoleucine via isoleucine precursor 2-oxobutanoate generated from threonine, this pathway accounts for a minor fraction of isoleucine biosynthesis, while the majority of isoleucine is instead derived from acetyl-coenzyme A and pyruvate, possibly via the citramalate pathway, overview | 2-oxobutanoate + NH3 | - |
? | |
L-threonine | Geobacter sulfurreducens DSM 12127 | a step in the pathway for the biosynthesis of isoleucine via isoleucine precursor 2-oxobutanoate generated from threonine, this pathway accounts for a minor fraction of isoleucine biosynthesis, while the majority of isoleucine is instead derived from acetyl-coenzyme A and pyruvate, possibly via the citramalate pathway, overview | 2-oxobutanoate + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacter sulfurreducens | Q74FW6 | strain DL-1, ATCC 51573, gene GSU0486 or tcdB | - |
Geobacter sulfurreducens DSM 12127 | Q74FW6 | strain DL-1, ATCC 51573, gene GSU0486 or tcdB | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.189 | - |
strain DL-1 | Geobacter sulfurreducens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-threonine | - |
Geobacter sulfurreducens | 2-oxobutanoate + NH3 | - |
? | |
L-threonine | a step in the pathway for the biosynthesis of isoleucine via isoleucine precursor 2-oxobutanoate generated from threonine, this pathway accounts for a minor fraction of isoleucine biosynthesis, while the majority of isoleucine is instead derived from acetyl-coenzyme A and pyruvate, possibly via the citramalate pathway, overview | Geobacter sulfurreducens | 2-oxobutanoate + NH3 | - |
? | |
L-threonine | - |
Geobacter sulfurreducens DSM 12127 | 2-oxobutanoate + NH3 | - |
? | |
L-threonine | a step in the pathway for the biosynthesis of isoleucine via isoleucine precursor 2-oxobutanoate generated from threonine, this pathway accounts for a minor fraction of isoleucine biosynthesis, while the majority of isoleucine is instead derived from acetyl-coenzyme A and pyruvate, possibly via the citramalate pathway, overview | Geobacter sulfurreducens DSM 12127 | 2-oxobutanoate + NH3 | - |
? | |
additional information | GSU0486 also catalyzes the deamination of L-serine, EC 4.3.1.17 | Geobacter sulfurreducens | ? | - |
? | |
additional information | GSU0486 also catalyzes the deamination of L-serine, EC 4.3.1.17 | Geobacter sulfurreducens DSM 12127 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GSU0486 | - |
Geobacter sulfurreducens |
tdcB | - |
Geobacter sulfurreducens |
Thr ammonia-lyase | - |
Geobacter sulfurreducens |
threonine ammonia-lyase | - |
Geobacter sulfurreducens |