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Literature summary for 4.3.1.19 extracted from

  • Szamosi, I.; Shaner, D.L.; Singh, B.K.
    Identification and characterization of a biodegradative form of threonine dehydratase in senescing tomato (Lycopersicon esculentum) leaf (1993), Plant Physiol., 101, 999-1004.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.3.1.19

Inhibitors

Inhibitors Comment Organism Structure
Ile 2 different forms: one enzyme form is sensitive to inhibition by Ile, the other form is insensitive to inhibition by Ile Solanum lycopersicum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.25
-
 L-Thr Ile-sensitive enzyme form and Ile-insensitive form Solanum lycopersicum
0.25
-
 L-Ser Ile-insensitive enzyme form Solanum lycopersicum
1.7
-
 L-Ser Ile-sensitive form Solanum lycopersicum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
200000
-
 Ile-insensitive enzyme form, gel filtration Solanum lycopersicum
370000
-
 Ile-sensitive enzyme form, gel filtration Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Thr Solanum lycopersicum key enzyme in biosynthesis of Ile ?
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum
-
 2 different forms: one enzyme form is sensitive to inhibition by Ile, the other form is insensitive to inhibition by Ile
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf isoleucine-sensitive enzyme form occurs predominantly in younger leaves, isoleucine-insensitive enzyme form occurs predominantly in older leaves Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ser
-
 Solanum lycopersicum pyruvate + NH3
-
 ?
L-Thr key enzyme in biosynthesis of Ile Solanum lycopersicum ?
-
 ?
L-threonine
-
 Solanum lycopersicum 2-oxobutanoate + NH3
-
 ?