Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.3.1.19 extracted from

  • Shizuta, Y.; Hayaishi, O.
    Regulation of biodegradative threonine deaminase (1976), Curr. Top. Cell. Regul., 11, 99-146.
    View publication on PubMed
Search for more literature for 4.3.1.19

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5
-
 L-Ser in presence of AMP Escherichia coli
11
-
 L-Thr in presence of AMP Escherichia coli
40
-
 L-Ser in absence of AMP Escherichia coli
91
-
 L-Thr in absence of AMP Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
147000
-
 sedimentation equilibrium ultracentrifugation Escherichia coli
184000
-
-
 Clostridium tetanomorphum

Organism

Organism UniProt Comment Textmining
Clostridium tetanomorphum
-
-
-
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ser
-
 Escherichia coli pyruvate + NH3
-
 ?
L-threonine
-
 Escherichia coli 2-oxobutanoate + NH3
-
 ?
L-threonine
-
 Clostridium tetanomorphum 2-oxobutanoate + NH3
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4 9.2 in presence of AMP Escherichia coli
9 9.8 in absence of AMP Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ADP activates Clostridium tetanomorphum
AMP activates Escherichia coli
pyridoxal 5'-phosphate contains 4 mol of pyridoxal 5'-phosphate per mol of enzyme Escherichia coli
pyridoxal 5'-phosphate contains 4 mol of pyridoxal 5'-phosphate per mol of enzyme Clostridium tetanomorphum
pyridoxal 5'-phosphate cofactor Escherichia coli
pyridoxal 5'-phosphate cofactor Clostridium tetanomorphum