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Literature summary for 4.3.1.19 extracted from

  • Bell, S.C.; Turner, J.M.
    Bacterial catabolism of threonine. Threonine degradation initiated by L-threonine hydro-lyase (deaminating) in a species of Corynebacterium (1977), Biochem. J., 164, 579-587.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
L-Val activates Corynebacterium sp.

Inhibitors

Inhibitors Comment Organism Structure
Ile 0.06 mM, 50% inhibition Corynebacterium sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Thr Corynebacterium sp. constitutive enzyme ?
-
?
L-Thr Corynebacterium sp. F5 / NCIMB 11102 constitutive enzyme ?
-
?

Organism

Organism UniProt Comment Textmining
Corynebacterium sp.
-
-
-
Corynebacterium sp. F5 / NCIMB 11102
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Corynebacterium sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Corynebacterium sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-allothreonine 5% of the activity L-Thr Corynebacterium sp. ?
-
?
L-allothreonine 5% of the activity L-Thr Corynebacterium sp. F5 / NCIMB 11102 ?
-
?
L-serine 6% of the activity with L-Thr Corynebacterium sp. pyruvate + NH3
-
?
L-serine 6% of the activity with L-Thr Corynebacterium sp. F5 / NCIMB 11102 pyruvate + NH3
-
?
L-Thr constitutive enzyme Corynebacterium sp. ?
-
?
L-Thr constitutive enzyme Corynebacterium sp. F5 / NCIMB 11102 ?
-
?
L-threonine
-
Corynebacterium sp. 2-oxobutanoate + NH3
-
?
L-threonine
-
Corynebacterium sp. F5 / NCIMB 11102 2-oxobutanoate + NH3
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9 Tris/HCl buffer and diethanolamine buffer Corynebacterium sp.

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.06
-
Ile
-
Corynebacterium sp.